130th Iowa Academy of Science Annual Meeting

April 20 - 21, 2018
Buena Vista University
Storm Lake, Iowa


Proceedings of the 130th Annual Meeting

Abstracts will be published in the Proceedings and the Journal of the Iowa Academy of Science.

The 130th IAS Annual Meeting Proceedings will be printed and distributed to all registered attendees at the Annual Meeting. The Proceedings will include abstracts for oral and poster presentations by scientists, graduate and undergraduate students. Also included will be research presentations by middle and high school students from the Iowa Junior Academy of science.  It will also include the Annual Meeting schedule. Attendees will be able to access additional session information using their smart phone.


General Sessions and Symposiums
130th Annual Meeting
Buena Vista University
Storm Lake, Iowa
April 20 - 21, 2018


General Session I

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Buena Vista University
Storm Lake, Iowa

Speaker


General Session II

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Buena Vista University
Storm Lake, Iowa

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General Session III

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Buena Vista University
Storm Lake, Iowa

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Symposium A

 


Room TBA
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Buena Vista University
Storm Lake, Iowa

 

Gene editing in Eukaryotes and Prokaryotes

CRISPR/Cas9-mediated gene editing is a promising new technology utilized to disrupt or edit genes in living cells. It has been used successfully in a wide array of organisms including bacteria, plants, flies,  zebrafish, fungi, mice, and recently, human embryos. In model organisms, gene editing further enhances our ability to study gene function over existing methods by allowing specific mutations to be incorporated into the endogenous copies of the gene. This reduces the possibility that observed phenotypes could be due to changes in protein expression levels. The ability to edit genes in living cells, including stem cells and embryos, opens the door to advances in human medicine including the repair of disease causing alleles in the embryo stage, and the modification of specific cell types, such as CD4+ T cells, to render them immune to infection by HIV or other pathogens. This symposium is intended to explain gene editing and the CRISPR/Cas9 system for those who will be discussing it in the classroom but have not yet had the opportunity to use it, and to render it more accessible to researchers who are interested in using the technology in the

Presentations

Title

Melissa M. Harrison, Ph.D.

For over 100 years, studies of Drosophila melanogaster have provided essential insights into development and disease. Until recently it was nearly impossible to make precise edits to the genome. Cas9-mediated genome editing has enabled an unprecedented ability to modify the genome of Drosophila. We will discuss practical considerations for modifying the genome of a metazoan and how these modifications can be used to address fundamental biological questions as well as model disease.

Biography

 

 

Title

Eric B. Taylor, Ph.D.

Mitochondria are the energetic hub of the eukaryotic cell. To work, they must move small molecules across the inner membrane, in and out of the matrix.  How the system of mitochondrial transporters, called carriers, functions in living cells is not well understood. Functional redundancy within the mitochondrial carrier system makes deciphering the role of single carriers challenging.  We have developed a novel CRISPR-based approach to rapidly detect carrier functional interactions. We will outline this approach and some resultant discoveries.

Biography


Title

Dipali Sashital, Ph.D.

 

CRISPR/Cas9 originates from a prokaryotic immune system, which protects bacteria from infection by viruses and other invaders. In addition to providing revolutionary genome editing tools, fundamental research into CRISPR/Cas systems has deepened our understanding of the complex molecular warfare that occurs between bacteria and their invaders. We will present mechanistic insights into CRISPR/Cas systems that will enable improved tool development and reveal how bacteria adapt to rapidly evolving viruses.

Biography


 

Symposium B

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Buena Vista University
Storm Lake, Iowa

             

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Symposium C - Workshop

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Buena Vista University
Storm Lake, Iowa

 

Description of the Workshop

 

 

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